- ≥99% HPLC purity
- Lot-matched certificate of analysis
- Ships next business day, tracked
Kisspeptin-10 Nasal Spray
Pre-mixed Kisspeptin-10 solution in a metered intranasal pump bottle
- FormPre-mixed aqueous solution, amber bottle with metered nasal pump
- Research areasHPG-axis signalling, GnRH pulse generation, intranasal delivery and mucosal absorption
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
This is Kisspeptin-10 supplied as a ready-mixed aqueous solution in an amber bottle fitted with a metered nasal pump, rather than as a lyophilized vial. Kisspeptin-10 is the C-terminal decapeptide fragment of the KISS1 gene product, an RFamide-family peptide that acts as an agonist at KISS1R (formerly GPR54) and sits upstream of GnRH neurons in the hypothalamic–pituitary–gonadal axis.
The molecule is identical to the vial product; only the presentation differs. Because the solution is already prepared, there is no weighing, reconstitution or diluent-handling step, and each actuation delivers a fixed volume, which makes the format convenient for intranasal delivery and mucosal-absorption research where reproducible per-spray volumes matter more than fine mass adjustment. The trade-off is that an aqueous peptide solution is less stable than a sealed lyophilized cake, so the in-use window is shorter and refrigerated storage is required.
Specifications
Identity
- Amino acid sequence
- Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Supply & purity
- Form
- Pre-mixed aqueous solution, amber bottle with metered nasal pump
- Available sizes
- 15 mL containing 10 mg; 30 mL containing 20 mg
Additional detail
- Nominal concentration
- ≈0.67 mg/mL in both fills
- Metered delivery
- Pump typically dispenses ≈0.1 mL per actuation once primed
- Active component
- Kisspeptin-10 (KP-10, metastin 45–54), ≥99% by HPLC
- CAS number (active)
- 374675-21-5
- Molecular formula (active)
- C63H83N17O14
- Molecular weight (active)
- 1302.47 g/mol
- Receptor target
- KISS1R (GPR54), a Gq/11-coupled class A GPCR
- Vehicle
- Aqueous, preserved for multi-actuation handling; clear and colourless when fresh
- Research areas
- HPG-axis signalling, GnRH pulse generation, intranasal delivery and mucosal absorption
- Storage
- 2–8 °C upright, protected from light; do not freeze the filled bottle
Questions about Kisspeptin-10 Nasal Spray
How does the spray differ from the lyophilized vial?
The molecule is identical. The spray is a ready-mixed aqueous solution in a metered pump, so there is no reconstitution step, but the trade-off is a shorter usable life and mandatory refrigeration. The vial gives finer control over concentration and much longer storage stability.
How much peptide is in each bottle?
The 15 mL bottle contains 10 mg of Kisspeptin-10 and the 30 mL bottle contains 20 mg, so both sit at roughly 0.67 mg per millilitre. A primed metered pump typically dispenses about 0.1 mL per actuation, which corresponds to approximately 67 micrograms of peptide.
What purity documentation is available?
The Kisspeptin-10 used in the fill is tested by HPLC to at least 99% purity with identity confirmed by mass spectrometry, and a lot-matched certificate of analysis is available. The COA covers the peptide raw material used for the specific fill lot shipped.
What does Kisspeptin-10 act on?
It is an agonist at KISS1R, also called GPR54, a Gq/11-coupled receptor expressed on GnRH neurons in the hypothalamus. That places it upstream of the reproductive axis, which is why it appears in HPG-axis, puberty-onset and gonadotropin-pulse research.
Can the bottle be frozen for longer storage?
No. Freezing risks cracking the glass, distorting the pump and stressing the peptide through ice-front concentration effects. Keep it refrigerated at 2–8 °C, upright and out of direct light, and plan the study around the limited in-use window instead.
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