- ≥99% HPLC purity
- Lot-matched certificate of analysis
- Ships next business day, tracked
Semax Nasal Spray
Pre-mixed Semax heptapeptide research solution, 15 mL metered spray bottle
- FormPre-mixed aqueous solution, 15 mL bottle with metered spray pump
- Mol. weight813.93 g/mol
- Research areasBDNF and NGF expression, TrkB signalling, attention and memory paradigms, cerebral ischaemia models
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
Semax Nasal Spray supplies the synthetic heptapeptide Semax (CAS 80714-61-0, Met-Glu-His-Phe-Pro-Gly-Pro) as a ready-to-use aqueous solution in a 15 mL bottle with a metered pump. Semax was developed from the ACTH(4–10) fragment of adrenocorticotropic hormone by appending Pro-Gly-Pro to the C-terminus. That single design change does two things: it strips out the corticotropic activity of the parent hormone, and it shields the peptide from the exopeptidases that would otherwise clear a short linear sequence within minutes.
Two fills are offered in the same 15 mL bottle — 10 mg total, which is roughly 0.67 mg/mL, and 20 mg total, roughly 1.33 mg/mL. Because the solution is pre-formulated, laboratories comparing intranasal delivery against parenteral or oral formats can work from a documented concentration without a weighing and reconstitution step in between, which removes one common source of between-session variance.
Specifications
Identity
- CAS number
- 80714-61-0
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.93 g/mol
- Amino acid sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
- Peptide class
- Synthetic ACTH(4–10) fragment analogue (heptapeptide)
Supply & purity
- Form
- Pre-mixed aqueous solution, 15 mL bottle with metered spray pump
- Available sizes
- 15 mL (10 mg total), 15 mL (20 mg total)
Additional detail
- Concentration
- Approximately 0.67 mg/mL (10 mg fill) or 1.33 mg/mL (20 mg fill)
- Purity (raw material)
- ≥99% by HPLC; lot-matched COA available
- Amino acid count
- 7 residues
- Research areas
- BDNF and NGF expression, TrkB signalling, attention and memory paradigms, cerebral ischaemia models
- Reconstitution
- None required — supplied pre-mixed and ready to dispense
- Storage
- 2–8 °C, upright, protected from light; do not freeze the filled bottle
Questions about Semax Nasal Spray
How much Semax is in each bottle?
Both options use a 15 mL bottle. The 10 mg fill works out to roughly 0.67 mg/mL and the 20 mg fill to roughly 1.33 mg/mL. The exact concentration is printed on the label and restated on the lot-matched Certificate of Analysis for the batch you receive.
Is the Semax third-party tested with a COA?
Yes. The peptide used in the formulation is third-party analysed by HPLC to ≥99% purity with mass-spectrometry identity confirmation, and a lot-matched Certificate of Analysis is available. Always match the lot number on the bottle to the COA before recording data.
What is Semax chemically?
A synthetic heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro, CAS 80714-61-0, formula C37H51N9O10S, molecular weight 813.93 g/mol. It is an analogue of the ACTH(4–10) fragment extended with Pro-Gly-Pro, which slows enzymatic degradation without retaining adrenal-stimulating activity.
Does the spray need reconstitution?
No. It ships pre-mixed and ready to dispense, which is the main practical difference from the lyophilized Semax vial. Removing the reconstitution step removes weighing and dilution error from experiments that compare formats or delivery routes.
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