Purity (raw material): ≥99% by HPLC
Lot-matched certificate of analysis
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Semax Nasal Spray

Pre-mixed Semax heptapeptide research solution, 15 mL metered spray bottle

In stock·2 formats available·CAS 80714-61-0

$85Range $85 – $140

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15 mL · 10 mg$8515 mL · 20 mg$140

Ask about this listing or request its COA

FormPre-mixed aqueous solution, 15 mL bottle with metered spray pump
Mol. weight813.93 g/mol
Research areasBDNF and NGF expression, TrkB signalling, attention and memory paradigms, cerebral ischaemia models

Overview

Semax Nasal Spray supplies the synthetic heptapeptide Semax (CAS 80714-61-0, Met-Glu-His-Phe-Pro-Gly-Pro) as a ready-to-use aqueous solution in a 15 mL bottle with a metered pump. Semax was developed from the ACTH(4–10) fragment of adrenocorticotropic hormone by appending Pro-Gly-Pro to the C-terminus. That single design change does two things: it strips out the corticotropic activity of the parent hormone, and it shields the peptide from the exopeptidases that would otherwise clear a short linear sequence within minutes.

Two fills are offered in the same 15 mL bottle — 10 mg total, which is roughly 0.67 mg/mL, and 20 mg total, roughly 1.33 mg/mL. Because the solution is pre-formulated, laboratories comparing intranasal delivery against parenteral or oral formats can work from a documented concentration without a weighing and reconstitution step in between, which removes one common source of between-session variance.

Specifications

Identity

CAS number: 80714-61-0
Molecular formula: C37H51N9O10S
Molecular weight: 813.93 g/mol
Amino acid sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Peptide class: Synthetic ACTH(4–10) fragment analogue (heptapeptide)

Supply & purity

Form: Pre-mixed aqueous solution, 15 mL bottle with metered spray pump
Available sizes: 15 mL (10 mg total), 15 mL (20 mg total)

Additional detail

Concentration: Approximately 0.67 mg/mL (10 mg fill) or 1.33 mg/mL (20 mg fill)
Purity (raw material): ≥99% by HPLC; lot-matched COA available
Amino acid count: 7 residues
Research areas: BDNF and NGF expression, TrkB signalling, attention and memory paradigms, cerebral ischaemia models
Reconstitution: None required — supplied pre-mixed and ready to dispense
Storage: 2–8 °C, upright, protected from light; do not freeze the filled bottle

Units and conversions

This is a pre-mixed presentation: the strength is fixed at fill, and the only arithmetic between the label and the bench is a change of units. The peptide unit converter moves between mg, mcg, mL and µL without the decimal-point slip that costs a whole run.

Certificate of analysis

Every lot of Semax Nasal Spray is released against a certificate of analysis: the batch-specific laboratory data for that lot, not a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.

Purity (raw material): ≥99% by HPLC — the specification for this listing. The figure for the lot you receive is the one reported on that lot’s certificate.

No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.

Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.

Questions about Semax Nasal Spray

How much Semax is in each bottle?

Both options use a 15 mL bottle. The 10 mg fill works out to roughly 0.67 mg/mL and the 20 mg fill to roughly 1.33 mg/mL. The exact concentration is printed on the label and restated on the lot-matched Certificate of Analysis for the batch you receive.

Is the Semax third-party tested with a COA?

Yes. The peptide used in the formulation is third-party analysed by HPLC to ≥99% purity with mass-spectrometry identity confirmation, and a lot-matched Certificate of Analysis is available. Always match the lot number on the bottle to the COA before recording data.

What is Semax chemically?

A synthetic heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro, CAS 80714-61-0, formula C37H51N9O10S, molecular weight 813.93 g/mol. It is an analogue of the ACTH(4–10) fragment extended with Pro-Gly-Pro, which slows enzymatic degradation without retaining adrenal-stimulating activity.

Does the spray need reconstitution?

No. It ships pre-mixed and ready to dispense, which is the main practical difference from the lyophilized Semax vial. Removing the reconstitution step removes weighing and dilution error from experiments that compare formats or delivery routes.