- ≥98% by HPLC
- Lot-matched certificate of analysis
- Ships next business day, tracked
ACP-105
Non-steroidal selective androgen receptor modulator for laboratory study
- FormOral-format capsules in a sealed bottle with desiccant, or a 30 mL research liquid in a dropper bottle
- Mol. weight290.79 g/mol
- Research areasAR binding and transactivation assays, muscle and bone tissue selectivity, prostate-sparing profiles, rodent cognition and behaviour
Overview
ACP-105 is a small non-steroidal molecule catalogued under CAS 899821-23-9 with a molecular mass near 290.8 g/mol, developed within the selective androgen receptor modulator class. It is not a peptide and not a steroid: it is a compact synthetic organic compound built around a bicyclic amine core that binds the androgen receptor without sharing the four-ring steroid scaffold of testosterone or its derivatives.
Partial agonism is the property that determines how the compound gets used at the bench. A partial agonist produces a submaximal transactivation response even at saturating concentration, and in the presence of a full agonist it can behave as an antagonist, which makes compounds of this kind more useful for probing receptor conformation and coregulator recruitment than for maximising a response. Reported work covers androgen receptor binding and transactivation assays, tissue-selectivity comparisons across muscle, bone and prostate, and rodent cognition and behaviour endpoints. Solubility is the main practical constraint: stocks are made up in DMSO or ethanol and diluted into medium with vehicle concentration matched across wells. The 30 mL solution at 20 mg/mL exists for designs where volumetric dilution is more convenient than re-weighing powder.
Specifications
Identity
- CAS number
- 899821-23-9
- Molecular weight
- 290.79 g/mol
Supply & purity
- Form
- Oral-format capsules in a sealed bottle with desiccant, or a 30 mL research liquid in a dropper bottle
- Purity
- ≥98% by HPLC; lot-matched COA available
- Available sizes
- 10 mg × 60 capsules; 30 mL liquid at 20 mg/mL
- Solubility
- Poorly water-soluble; powder stocks are typically prepared in DMSO or ethanol, and the research liquid uses a solvent carrier
Additional detail
- Compound class
- Non-steroidal selective androgen receptor modulator (SARM)
- Molecular target
- Androgen receptor (NR3C4), a nuclear hormone receptor
- Reported activity
- Partial agonist at the androgen receptor in reported assay work
- Structural note
- Compact synthetic organic molecule with a bicyclic amine core; contains no steroid ring system and no amide backbone
- Research areas
- AR binding and transactivation assays, muscle and bone tissue selectivity, prostate-sparing profiles, rodent cognition and behaviour
- Regulatory status
- Not approved by FDA or EMA for any indication; SARMs are not lawful dietary ingredients in the United States
- Sport status
- Prohibited at all times under the WADA anabolic agents category (S1.2)
- Storage
- Room temperature, sealed, away from light, heat and humidity; refrigeration extends liquid stability
Units and conversions
There is no reconstitution step for a solid oral format: the mass per unit of ACP-105 is fixed on the label. Where a published method is written in micrograms and the label is in milligrams, the peptide unit converter does the conversion.
Certificate of analysis
Every lot of ACP-105 is released against a certificate of analysis: the batch-specific laboratory data for that lot, not a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.
Purity: ≥98% by HPLC — the specification for this listing. The figure for the lot you receive is the one reported on that lot’s certificate.
No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.
Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.
Questions about ACP-105
Is ACP-105 a peptide?
No. It is a small non-steroidal organic molecule of roughly 291 g/mol with no amino acid backbone. It belongs to the selective androgen receptor modulator class, which is chemically unrelated to the peptides in our catalogue even though it is often browsed alongside them.
How does it differ from RAD-140 or LGD-4033?
All three bind the androgen receptor without a steroid scaffold, but they differ in chemistry and reported pharmacology. ACP-105 is notably smaller and is described in the literature as a partial agonist, whereas RAD-140 and LGD-4033 are generally reported as more potent full or near-full agonists in the assays used.
What purity documentation is supplied?
Each lot is tested by HPLC to at least 98% and accompanied by a lot-matched certificate of analysis with identity confirmation. Quote the lot number printed on the bottle when requesting the document. Independent verification before assay work is good practice for any grey-market compound class.
Is ACP-105 legal to buy?
It can be supplied as a research chemical for laboratory use, but it is not approved as a drug and it is not a lawful dietary ingredient in the United States. Buyers are responsible for compliance with the rules that apply in their own jurisdiction.
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