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Sildenafil — Research Liquid
PDE5 inhibitor reference listing — 30 mL at 30 mg/mL, short-acting profile
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
Sildenafil is a selective inhibitor of phosphodiesterase type 5 (PDE5), the pyrazolo[4,3-d]pyrimidinone that emerged from Pfizer's angina programme in the early 1990s and was subsequently approved as Viagra for erectile dysfunction in 1998 and, at different strengths, as Revatio for pulmonary arterial hypertension. Those approvals are stated here as public regulatory facts, not as a recommendation of use.
This is a prescription-only medicine. The listing exists as an institutional and demonstration catalog reference, and the material is supplied only against a valid prescription or documented institutional authorisation. No sourcing route, administration guidance or dosing information is provided anywhere on this page or by our staff.
Chemically, the free base has the formula C22H30N6O4S and a molecular weight of 474.58 g/mol; the marketed oral solid is normally the citrate salt, which has a different CAS number and formula weight. In this listing the compound is presented as a 30 mL oral solution at 30 mg per millilitre. Because sildenafil is one of the best-characterised probes of the nitric-oxide–cGMP pathway, it also appears widely as a pharmacological tool in vascular, pulmonary and cardiac laboratory research.
Questions about Sildenafil — Research Liquid
Is this available without a prescription?
No. Sildenafil is a prescription-only medicine. This listing exists as an institutional and demonstration catalog reference, and material is supplied only against a valid prescription or documented institutional authorisation. We provide no route to obtain it outside that framework.
What is the difference between the free base and the citrate salt?
The free base, CAS 139755-83-2, has a molecular weight of 474.58 g/mol. Marketed oral tablets normally use sildenafil citrate, a salt with its own CAS number and higher formula weight. Concentrations quoted for a preparation should always state which form the figure refers to.
Why is it approved for two very different conditions?
Both approvals follow from the same mechanism. Inhibiting PDE5 prolongs cGMP signalling and smooth-muscle relaxation, which is relevant in penile vasculature and in the pulmonary arterial bed. The two indications carry separate marketing authorisations and different approved strengths.
Do you provide dosing information?
No. Dosing, titration and administration are matters for the prescribing clinician and the approved product labelling in the relevant jurisdiction. This page carries chemistry, mechanism, regulatory-status and storage facts only, and our staff do not advise on use.
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