- ≥99% by HPLC per component; lot-matched COA available
- Lot-matched certificate of analysis
- Ships next business day, tracked
BPC-157 + TB-500 (Wolverine Blend)
Pre-blended BPC-157 and TB-500 in a single lyophilized research vial
- FormCo-lyophilized powder blend, sealed glass vial
- Research areasSoft-tissue repair, tendon and ligament models, cell migration, angiogenesis
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
The Wolverine blend places two of the most studied repair-model peptides into one lyophilized vial: BPC-157, a fifteen-residue fragment of a gastric protection protein, and TB-500, the acetylated seven-residue actin-binding fragment of thymosin beta-4. The two are combined in equal amounts, so the 10 mg vial supplies 5 mg of each and the 20 mg vial supplies 10 mg of each.
Laboratories reach for a pre-blended vial when a protocol calls for both sequences at a fixed ratio and separate reconstitution would add handling steps, extra septum punctures and another source of pipetting error. Both peptides are synthesised individually, purified by reversed-phase HPLC to at least 99% and only then combined and co-lyophilized, so the certificate of analysis reports each component on its own rather than the mixture as a whole.
Research interest in the pairing comes from the fact that the two sequences are examined through different mechanisms in the same injury models — BPC-157 in gastrointestinal and tendon work with an angiogenic component, TB-500 in cell-migration and cytoskeletal work. Whether combining them produces effects beyond either alone has not been settled in the published literature. The blend is sold for laboratory research only.
Specifications
Supply & purity
- Form
- Co-lyophilized powder blend, sealed glass vial
- Purity
- ≥99% by HPLC per component; lot-matched COA available
- Available sizes
- 10 mg total (5 mg / 5 mg), 20 mg total (10 mg / 10 mg)
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
Additional detail
- Components
- BPC-157 and TB-500 (thymosin beta-4 17–23 fragment)
- Blend ratio
- 1:1 by mass
- BPC-157 CAS number
- 137525-51-0
- BPC-157 formula and mass
- C62H98N16O22, 1419.55 g/mol
- BPC-157 sequence
- Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- TB-500 CAS number
- 885340-08-9
- TB-500 formula and mass
- C38H68N10O14, 889.02 g/mol
- TB-500 sequence
- Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
- Research areas
- Soft-tissue repair, tendon and ligament models, cell migration, angiogenesis
Questions about BPC-157 + TB-500 (Wolverine Blend)
What is the Wolverine blend?
It is a single lyophilized vial containing BPC-157 and TB-500 in equal amounts. The 10 mg option supplies 5 mg of each peptide and the 20 mg option supplies 10 mg of each, so a laboratory reconstitutes once instead of preparing two separate vials.
Are the two peptides tested separately?
Yes. Each sequence is synthesised and purified to at least 99% by reversed-phase HPLC before blending, and the certificate of analysis reports purity and identity for BPC-157 and TB-500 individually rather than giving a single figure for the mixture.
Can the ratio be adjusted?
Not within the vial. The two peptides are co-lyophilized at a fixed 1:1 ratio, so diluting the reconstituted solution changes both concentrations together. Studies that need to vary the ratio between components should order BPC-157 and TB-500 as separate vials.
What does research use only mean for this blend?
The vial is sold exclusively for in-vitro and laboratory investigation by qualified personnel. It is not a drug, supplement or medical product, is not approved for human or veterinary administration, and ships without dosing, cycle or protocol instructions of any kind.
Related
