- ≥99% by HPLC per component; lot-matched COA available
- Lot-matched certificate of analysis
- Ships next business day, tracked
Ipamorelin + GHRP-2
Two GHS-R1a secretagogues co-lyophilized 1:1 in a 10 mg vial
- FormCo-lyophilized powder blend, sealed glass vial with crimped stopper
- Research areasGHS-R1a pharmacology, secretagogue potency and selectivity, somatotroph reserve, cortisol and prolactin cross-reactivity, IGF-1 axis
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
This vial holds two growth hormone secretagogues that act at the same receptor but were designed with different selectivity profiles. Ipamorelin is a pentapeptide with a C-terminal amide, sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, built from unnatural residues including 2-aminoisobutyric acid and D-2-naphthylalanine. GHRP-2, also catalogued as pralmorelin, is the second-generation hexapeptide of the growth hormone-releasing peptide series, sequence D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2. Both are agonists at the growth hormone secretagogue receptor 1a, the ghrelin receptor.
Specifications
Identity
- Peptide class
- Two growth hormone-releasing peptides (GHRPs), both GHS-R1a agonists
Supply & purity
- Form
- Co-lyophilized powder blend, sealed glass vial with crimped stopper
- Purity
- ≥99% by HPLC per component; lot-matched COA available
- Available sizes
- 10 mg total — 5 mg Ipamorelin / 5 mg GHRP-2
- Solubility
- Bacteriostatic or sterile water
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, protected from light, used within the study window
Additional detail
- Components
- Ipamorelin and GHRP-2 (pralmorelin)
- Blend ratio
- 1:1 by mass
- Ipamorelin CAS number
- 170851-70-4
- Ipamorelin formula and mass
- C38H49N9O5, 711.85 g/mol
- Ipamorelin sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- GHRP-2 CAS number
- 158861-67-7
- GHRP-2 formula and mass
- C45H55N9O6, 817.97 g/mol
- GHRP-2 sequence
- D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
- Also known as
- GHRP-2 is also catalogued as pralmorelin, KP-102 or GPA-748
- Primary target
- Growth hormone secretagogue receptor 1a (ghrelin receptor)
- Research areas
- GHS-R1a pharmacology, secretagogue potency and selectivity, somatotroph reserve, cortisol and prolactin cross-reactivity, IGF-1 axis
Questions about Ipamorelin + GHRP-2
How much of each peptide is in the vial?
The 10 mg fill is a 1:1 blend — 5 mg of Ipamorelin and 5 mg of GHRP-2. Because the masses are equal, a single reconstitution calculation gives the concentration of both. Exact loading is stated on the label and on the lot-matched certificate of analysis.
Do these two peptides act on different receptors?
No — both are agonists at the growth hormone secretagogue receptor 1a, the ghrelin receptor. That is what distinguishes this blend from GHRH-analogue combinations such as CJC-1295 with a GHRP, where two genuinely separate receptors on the same somatotroph are engaged.
What is the difference between Ipamorelin and GHRP-2?
Selectivity versus potency. Ipamorelin is a pentapeptide widely described as the most selective classic GHRP, with little reported effect on cortisol and prolactin. GHRP-2 is a hexapeptide generally reported as the more potent releaser on a molar basis, with more cross-reactivity at other pituitary outputs.
What documentation comes with the vial?
A lot-matched certificate of analysis covering both peptides, each reported separately with HPLC purity of at least 99% and mass-spectrometric identity confirmation. Quote the lot number printed on the vial when requesting the document.
Which diluent should be used?
Bacteriostatic water is standard for multi-draw laboratory preparations because the benzyl alcohol preservative supports repeated septum entry. Sterile water is appropriate for a single-use solution. Add the diluent down the vial wall, swirl rather than shake, and keep the reconstituted vial refrigerated.
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