≥99% by HPLC per vial; separate lot-matched COA for each
Lot-matched certificate of analysis
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Prime Stack (Tesamorelin · Ipamorelin · MOTS-c vials)

Three-vial performance kit: tesamorelin, ipamorelin and MOTS-c

In stock·1 format available

$144

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3-vial stack$144

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FormLyophilized powder in each vial, individually capped
Research areasGHRH receptor signalling, GHS-R1a pharmacology, AMPK and mitochondrial metabolism

Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.

Overview

The Prime Stack pairs the growth hormone axis with mitochondrial biology, supplying tesamorelin, ipamorelin and MOTS-c as three separately sealed lyophilized vials. Two of the three act on the pituitary through different receptors; the third operates at the level of the mitochondrion and has no relationship to the somatotropic axis at all.

Tesamorelin is a stabilised analogue of growth hormone-releasing hormone — the full GHRH(1-44) sequence carrying a trans-3-hexenoyl group at the N-terminus that resists dipeptidyl peptidase-4 cleavage. Ipamorelin is a five-residue agonist at the ghrelin receptor GHS-R1a, described in its original characterisation as selective, with limited movement of cortisol and prolactin in the animal models reported. MOTS-c is different in kind: a 16-residue peptide encoded within the mitochondrial 12S rRNA gene, studied in relation to AMPK signalling and metabolic homeostasis.

Keeping the three unmixed lets a study run each arm independently — GHRH receptor, ghrelin receptor and mitochondrial — or combine them in whatever ratio a design requires. Each vial is HPLC-assayed to ≥99% purity with its own lot-matched certificate of analysis. Supplied as research material for laboratory use only.

Specifications

Supply & purity

Form: Lyophilized powder in each vial, individually capped
Purity: ≥99% by HPLC per vial; separate lot-matched COA for each

Handling & storage

Storage (lyophilized): −20 °C, protected from light and moisture
Storage (reconstituted): 2–8 °C, protected from light

Additional detail

Product type: Multi-vial research kit — three separately sealed vials
Kit contents: One tesamorelin vial, one ipamorelin vial, one MOTS-c vial
Tesamorelin: CAS 218949-48-5 · C221H366N72O67S · 5135.86 g/mol
Ipamorelin: CAS 170851-70-4 · C38H49N9O5 · 711.85 g/mol
MOTS-c: CAS 1627580-64-6 · C101H152N28O22S2 · 2174.55 g/mol
Tesamorelin class: GHRH(1-44) analogue with N-terminal trans-3-hexenoyl group
Ipamorelin sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Research areas: GHRH receptor signalling, GHS-R1a pharmacology, AMPK and mitochondrial metabolism
Reconstitution: Each vial prepared separately at protocol-defined concentration

Questions about Prime Stack (Tesamorelin · Ipamorelin · MOTS-c vials)

How does tesamorelin differ from sermorelin?

Sermorelin is the truncated GHRH(1-29) fragment. Tesamorelin is the full 44-residue sequence with a trans-3-hexenoyl group at the N-terminus that resists DPP-4 cleavage. Both act at the GHRH receptor, but tesamorelin is the more stable molecule.

Why include MOTS-c with two GH-axis peptides?

Because it addresses a different level of biology. Tesamorelin and ipamorelin act on pituitary receptors; MOTS-c is a mitochondrial-derived peptide studied around AMPK and cellular energetics. The kit lets a panel cover endocrine and mitochondrial arms separately.

Does each vial come with its own COA?

Yes. Each vial is a distinct manufacturing lot released with its own certificate of analysis reporting HPLC identity and purity for that peptide. Three separate documents accompany the kit, and current lot COAs can be requested beforehand.

Which peptide needs the most careful handling?

Tesamorelin. At roughly 5,136 g/mol it is the largest molecule in the kit and the most vulnerable to shear damage, so bacteriostatic water should be added slowly down the vial wall and the vial swirled rather than shaken or vortexed.

Can the vials be used at different points in a study?

Yes. Unopened lyophilized vials stored sealed at −20 °C away from light and moisture remain stable well beyond a year, so components can be staged across study phases rather than all prepared at once.