- ≥99% HPLC purity
- Lot-matched certificate of analysis
- Ships next business day, tracked
Semaglutide Oral Research Tablets
Oral semaglutide research tablets with an SNAC-type absorption enhancer, 30 count
- FormCompressed tablet in a sealed bottle with desiccant and tamper-evident closure
- Mol. weight4113.58 g/mol
- Research areasOral peptide delivery, permeation enhancers, dissolution profiling, GLP-1 receptor pharmacology
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
These tablets present semaglutide, the acylated 31-residue GLP-1 receptor agonist analogue, in a solid oral research format instead of a lyophilized vial. The peptide itself is unchanged: same CAS number, same molecular formula, same Aib substitution at position 2 and the same gamma-Glu-(AEEA)2-C18 diacid chain conjugated at Lys26. What differs is everything around it. Peptides of this size are ordinarily destroyed by gastric acid and pepsin and absorb poorly across intestinal epithelium, so an oral presentation depends on a co-formulated permeation enhancer of the SNAC type (salcaprozate sodium) that transiently raises local pH and assists paracellular and transcellular passage.
Specifications
Identity
- CAS number
- 910463-68-2
- Molecular formula
- C187H291N45O59
- Molecular weight
- 4113.58 g/mol
- Peptide class
- Acylated GLP-1 receptor agonist analogue (incretin mimetic), 31 amino acids
Supply & purity
- Form
- Compressed tablet in a sealed bottle with desiccant and tamper-evident closure
Additional detail
- Semaglutide per tablet
- 3 mg or 7 mg, depending on the option selected
- Tablets per bottle
- 30
- Peptide purity
- ≥99% by HPLC for the peptide input; lot-matched COA available
- Key modifications
- Aib at position 2; Lys26 conjugated to gamma-Glu-(AEEA)2-C18 diacid
- Absorption enhancer
- SNAC-type carrier (salcaprozate sodium); the excipient set is stated on the lot label
- Research areas
- Oral peptide delivery, permeation enhancers, dissolution profiling, GLP-1 receptor pharmacology
- Storage
- Room temperature in the sealed bottle with desiccant, away from humidity and direct light
Questions about Semaglutide Oral Research Tablets
What is SNAC and why is it present?
SNAC (salcaprozate sodium) is an absorption enhancer used in oral peptide formulations. It buffers the local gastric environment against proteolysis and transiently assists the peptide across the epithelium near the eroding tablet. Its effect is local and short-lived.
What purity documentation is available?
The semaglutide used in these tablets is purified to ≥99% by HPLC and each lot carries a matched certificate of analysis for purity and identity. Quote the lot number printed on your bottle to receive the correct COA.
How should the tablets be stored?
Store the sealed bottle at room temperature with its desiccant, protected from humidity and direct light. No refrigeration or reconstitution is needed. Reseal promptly after each opening to limit moisture ingress.
Are these tablets a medicine?
No. They are a research material supplied for laboratory use only. They are not an approved drug product, are not dispensed against a prescription, and must not be taken by humans or given to animals.
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