- ≥99% by HPLC; lot-matched COA available
- Lot-matched certificate of analysis
- Ships next business day, tracked
PEG-MGF
PEGylated Mechano Growth Factor with extended in-solution stability
- FormLyophilized powder, sealed glass vial
- Mol. weightVaries with PEG chain length; stated on the lot certificate of analysis
- Research areasSkeletal-muscle remodelling, satellite-cell activation, repair kinetics, peptide half-life comparison
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
That difference is the entire reason PEG-MGF exists as a separate research article. Unmodified MGF is notoriously short-lived, which makes it awkward to use in whole-animal designs where a sustained exposure is needed. Investigators working on skeletal-muscle remodelling, satellite-cell dynamics and post-injury repair frequently run the two forms in parallel so that peptide half-life becomes a controlled variable rather than a confound.
MyPeptide supplies PEG-MGF as a lyophilized powder in a sealed glass vial, third-party tested by HPLC with a lot-matched certificate of analysis. Because PEGylation is a heterogeneous process, molecular weight varies with PEG chain length and is stated on the certificate for each lot rather than being quoted as a single fixed figure. Sold for laboratory research only.
Specifications
Identity
- Molecular weight
- Varies with PEG chain length; stated on the lot certificate of analysis
- Peptide class
- PEGylated IGF-1 splice-variant E-domain peptide
Supply & purity
- Form
- Lyophilized powder, sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Available sizes
- 2 mg, 5 mg
- Solubility
- Bacteriostatic or sterile water; PEGylation improves aqueous handling
Handling & storage
- Storage (lyophilized)
- −20 °C, protected from light and moisture
- Storage (reconstituted)
- 2–8 °C for short-term work; aliquot and freeze for longer studies
Additional detail
- Core peptide
- MGF, the 24-residue C-terminal E-domain of IGF-1 Ec
- Core amino acid sequence
- Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys
- Modification
- Covalently attached polyethylene glycol (PEG) chain
- Research areas
- Skeletal-muscle remodelling, satellite-cell activation, repair kinetics, peptide half-life comparison
Questions about PEG-MGF
What is the difference between PEG-MGF and MGF?
The peptide sequence is identical — both are the 24-residue IGF-1 Ec E-domain. PEG-MGF carries a polyethylene glycol chain that slows proteolysis and renal clearance, giving a much longer window of availability. Researchers usually choose between them based on the exposure duration a study design requires.
Why is no single molecular weight listed?
PEGylation attaches a polymer that itself has a mass distribution, so PEG-MGF is a family of closely related species rather than one exact molecular weight. The lot certificate of analysis reports the peptide content and the PEG specification for the material you receive.
Is this product third-party tested?
Yes. Each lot is tested by an independent laboratory with HPLC for purity and mass spectrometry for identity of the core peptide. The resulting certificate of analysis is matched to the lot number on your vial and available on request.
What is in the vial and what else do I need?
The vial contains only sterile-filtered lyophilized PEG-MGF under a vacuum seal — no diluent, syringes or filters are included. Bacteriostatic water and reconstitution supplies are listed separately in our lab supplies category.
How stable is PEG-MGF once reconstituted?
More stable than unmodified MGF, but still a peptide in aqueous solution. Hold reconstituted material at 2–8 °C for short-term work, protect it from light and repeated warming, and aliquot then freeze for anything running longer than a few days.
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