- ≥99% by HPLC per component
- Lot-matched certificate of analysis
- Ships next business day, tracked
Sleep Stack (DSIP · Epitalon · Melatonin)
Three-vial research kit: DSIP, Epitalon and melatonin for sleep-model work
- FormLyophilized powder in each vial, sealed with crimped stopper
- Research areasEEG sleep architecture, circadian phase and melatonin rhythm, pineal bioregulator studies, MT1/MT2 receptor work
Overview
The Sleep Stack brings together three compounds that appear repeatedly in circadian and sleep-architecture research, supplied as three separately sealed lyophilized vials rather than a premixed blend. Delta sleep-inducing peptide (DSIP) is an endogenous nonapeptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, isolated from rabbit cerebral venous blood during slow-wave sleep and studied since the 1970s for its association with EEG delta activity. Epitalon is the synthetic AEDG tetrapeptide derived from pineal extract research, examined for effects on melatonin rhythm and telomerase activity. Melatonin itself, N-acetyl-5-methoxytryptamine, is the pineal indoleamine that sets the darkness signal in vertebrate circadian systems.
Grouping them makes sense as a research panel because each addresses a different layer of the same system: melatonin is the timing hormone, Epitalon is studied as a modulator of the pineal machinery that produces it, and DSIP is investigated at the level of sleep-stage electrophysiology rather than clock phase. A study using all three can compare a direct signal, an upstream regulator and an independent sleep-associated peptide within one experimental design.
Specifications
Supply & purity
- Form
- Lyophilized powder in each vial, sealed with crimped stopper
- Purity
- ≥99% by HPLC per component; lot-matched COA for each vial
Handling & storage
- Storage (lyophilized)
- −20 °C, protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, aliquoted, protected from light; melatonin solutions are light-sensitive
Additional detail
- Kit contents
- 3 separately sealed lyophilized vials — DSIP, Epitalon, melatonin
- DSIP profile
- CAS 62568-57-4, C35H48N10O15, 848.81 g/mol — nonapeptide WAGGDASGE
- Epitalon profile
- CAS 307297-39-8, C14H22N4O9, 390.35 g/mol — tetrapeptide Ala-Glu-Asp-Gly
- Melatonin profile
- CAS 73-31-4, C13H16N2O2, 232.28 g/mol — N-acetyl-5-methoxytryptamine
- Reconstitution
- Each vial dissolved separately in bacteriostatic or sterile water; melatonin may need a co-solvent
- Research areas
- EEG sleep architecture, circadian phase and melatonin rhythm, pineal bioregulator studies, MT1/MT2 receptor work
- Shipping
- Ships as one package from a US facility with tracking
- Documentation
- Individual certificate of analysis available for each lot in the kit
Working out the concentration
Because Sleep Stack (DSIP · Epitalon · Melatonin) arrives dry, its concentration is a decision rather than a specification. Run the numbers through the reconstitution calculator — vial mass in, diluent volume in, mg/mL and mass per syringe unit out.
Certificate of analysis
Every lot of Sleep Stack (DSIP · Epitalon · Melatonin) is released against a certificate of analysis: the batch-specific laboratory data for that lot, not a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.
Purity: ≥99% by HPLC per component — the specification for this listing. The figure for the lot you receive is the one reported on that lot’s certificate.
No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.
Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.
Questions about Sleep Stack (DSIP · Epitalon · Melatonin)
Which compounds are included?
DSIP (delta sleep-inducing peptide, the nonapeptide WAGGDASGE), Epitalon (the AEDG tetrapeptide bioregulator) and melatonin (N-acetyl-5-methoxytryptamine). Each is a distinct research target: sleep-stage electrophysiology, pineal regulation and MT1/MT2 receptor signalling respectively.
Are certificates of analysis included?
Yes. Every vial carries its own lot number and matching COA covering HPLC purity and mass-spectrometric identity confirmation for the peptide components. Request copies by lot number and keep them filed with your experimental records.
Why does melatonin need different handling?
Melatonin is poorly soluble in water compared with the two peptides, so laboratories typically use a small co-solvent fraction to prepare stock. It is also light-sensitive in solution. Any co-solvent used must appear identically in vehicle controls or it becomes an uncontrolled variable.
Can the three be combined in one solution?
They are supplied separately precisely so that combination is an experimental decision rather than a fixed formulation. If a study calls for co-administration, prepare each solution independently first, verify compatibility at working concentration and always run single-agent arms alongside.
Is this kit for personal use?
No. Every component is supplied strictly for laboratory research.
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