- ≥99% by HPLC
- Lot-matched certificate of analysis
- Ships next business day, tracked
Vilon
Lys-Glu (KE) dipeptide bioregulator used in immune and ageing research models
- FormLyophilized powder in a sealed glass vial
- Mol. weight291.30 g/mol
- Research areasImmune-cell models, lymphocyte chromatin, thymic tissue, rodent ageing studies
Overview
Vilon is a linear dipeptide made of L-lysine and L-glutamic acid (Lys-Glu, or KE) with free N- and C-termini. It is the shortest compound in the Khavinson bioregulator series and the historical starting point for the whole class: researchers at the St. Petersburg Institute of Bioregulation and Gerontology were studying thymus-derived peptide extracts when they isolated and then synthesised the minimal active sequence, producing a molecule that can be made reproducibly and characterised precisely.
Because it is only two residues long, Vilon is often used as the reference case in structural work on ultrashort peptides. Its small size makes it convenient for modelling studies of peptide-DNA recognition and for experiments asking how little sequence information is needed before a peptide shows selectivity in a biological assay. Reports from this line of work describe effects on chromatin packing in cultured lymphocytes and on the expression of a limited set of immune-related transcripts.
Typical laboratory use centres on immunological cell models, thymic tissue preparations, and rodent ageing experiments in which survival curves, tumour incidence, and immune markers are tracked over long periods. Our Vilon is supplied as a 20 mg lyophilized vial, synthesised by SPPS, purified by HPLC to a ≥99% specification, and shipped with a lot-matched certificate of analysis.
Specifications
Identity
- CAS number
- 79443-38-8
- Molecular weight
- 291.30 g/mol
- Amino acid sequence
- Lys-Glu (KE), linear dipeptide with free N- and C-termini
- Peptide class
- Khavinson short-peptide bioregulator (dipeptide)
Supply & purity
- Form
- Lyophilized powder in a sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Available sizes
- 20 mg
- Solubility
- Bacteriostatic or sterile water; readily soluble in aqueous buffers
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, protected from light; use within the study window
Additional detail
- Tissue association
- Thymus peptide preparations
- Research areas
- Immune-cell models, lymphocyte chromatin, thymic tissue, rodent ageing studies
Working out the concentration
Reconstitution is where the arithmetic lives. The same vial made up with 1 mL or with 3 mL of diluent gives three-fold different numbers, which is why a reconstitution volume calculator is more use here than a fixed table: enter the vial mass and your diluent volume and read the concentration back.
For work specified in µM or nM rather than mg/mL, feed 291.30 g/mol and your volume into the peptide molarity calculator.
Certificate of analysis
Every lot of Vilon is released against a certificate of analysis: the batch-specific laboratory data for that lot, not a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.
Purity: ≥99% by HPLC — the specification for this listing. The figure for the lot you receive is the one reported on that lot’s certificate.
No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.
Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.
Questions about Vilon
What is Vilon?
Vilon is the synthetic dipeptide Lys-Glu (KE), the shortest member of the Khavinson short-peptide bioregulator family. It is supplied as a lyophilized powder in a sealed vial with a lot-matched certificate of analysis.
Is a certificate of analysis available?
Yes. Each lot is HPLC tested against a ≥99% purity specification and a lot-matched COA can be provided before or after purchase. The document records the batch identifier, purity result, identity confirmation, and physical description.
Why is Vilon only two amino acids long?
It came from an effort to identify the shortest active fragment of thymus peptide extracts. Reducing the extract to a defined two-residue sequence gave researchers a molecule that can be synthesised identically batch after batch and characterised by standard analytical methods.
How is it stored and shipped?
Vials are shipped from a United States facility in protective packaging. Store the lyophilized powder at −20 °C away from light and moisture, and keep reconstituted solution at 2–8 °C for the duration of the planned study window.
What sizes are offered?
Vilon is stocked as a single 20 mg lyophilized vial, the standard research quantity across this bioregulator series, which keeps comparisons between peptides in the same family straightforward.
