- ≥99% by HPLC; lot-matched COA available
- Lot-matched certificate of analysis
- Ships next business day, tracked
Crystagen
Glu-Asp-Pro (EDP) tripeptide bioregulator studied in immune-system models
- FormLyophilized powder in a sealed glass vial
- Mol. weight359.33 g/mol
- Research areasImmune-cell models, lymphocyte function assays, chromatin and gene-expression studies, rodent ageing models
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
Crystagen is a synthetic linear tripeptide with the sequence Glu-Asp-Pro, abbreviated EDP, supplied as a 20 mg lyophilized vial. It belongs to the family of short peptide bioregulators developed at the St Petersburg Institute of Bioregulation and Gerontology under Vladimir Khavinson, whose programme derived low-molecular-weight peptide fractions from animal tissues and then identified short synthetic sequences intended to reproduce their activity.
Within that family Crystagen is catalogued as the immune-system peptide, the synthetic counterpart of the thymic preparations represented in our range by Thymalin. Its structural relatives are easy to place: Vilon is the Lys-Glu dipeptide associated with the same tissue, while Cortagen (Ala-Glu-Asp-Pro), Cardiogen (Ala-Glu-Asp-Arg) and Bronchogen (Ala-Glu-Asp-Leu) share the Ala-Glu-Asp core. Crystagen's own sequence overlaps with Cortagen's final three residues, which makes the pair useful in comparative work.
Specifications
Identity
- Molecular formula
- C14H21N3O8
- Molecular weight
- 359.33 g/mol
- Amino acid sequence
- Glu-Asp-Pro (EDP), linear tripeptide with free N- and C-termini
- Peptide class
- Khavinson short-peptide bioregulator (tripeptide)
Supply & purity
- Form
- Lyophilized powder in a sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Solubility
- Bacteriostatic or sterile water; readily soluble in aqueous buffers
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, protected from light; use within the study window
Additional detail
- Available size
- 20 mg
- Tissue association
- Immune-system peptide preparations; synthetic counterpart to thymic fractions
- Sequence relationship
- Corresponds to the C-terminal three residues of Cortagen (Ala-Glu-Asp-Pro)
- Charge character
- Two acidic side chains (Glu, Asp) plus a conformationally restrictive proline — strongly anionic at neutral pH
- Research areas
- Immune-cell models, lymphocyte function assays, chromatin and gene-expression studies, rodent ageing models
Questions about Crystagen
What is Crystagen's sequence?
It is the linear tripeptide Glu-Asp-Pro, abbreviated EDP, with free N- and C-termini and a calculated mass of about 359.3 g/mol. The sequence corresponds to the final three residues of Cortagen, which makes the two useful to compare directly.
How does it differ from Thymalin?
Thymalin is a tissue-derived polypeptide complex containing many peptide species and has no single defined mass or sequence. Crystagen is one defined synthetic tripeptide. They are associated with the same tissue system, but chemically they are entirely different kinds of material.
What purity documentation is supplied?
Each lot is analysed by reverse-phase HPLC to at least 99% purity with mass-spectrometric identity confirmation, and a lot-matched certificate of analysis is available on request against the vial's lot number. Mass spectrometry matters here because short peptides absorb UV weakly.
How should it be reconstituted and stored?
It dissolves readily in bacteriostatic or sterile water with gentle swirling; no organic solvent is required. Keep the lyophilized vial at −20 °C away from light and moisture, and hold reconstituted solution at 2–8 °C, protected from light, for the duration of the study window.
