- ≥99% by HPLC
- Lot-matched certificate of analysis
- Ships next business day, tracked
Crystagen
Glu-Asp-Pro (EDP) tripeptide bioregulator studied in immune-system models
- FormLyophilized powder in a sealed glass vial
- Mol. weight359.33 g/mol
- Research areasImmune-cell models, lymphocyte function assays, chromatin and gene-expression studies, rodent ageing models
Overview
Crystagen is a synthetic linear tripeptide with the sequence Glu-Asp-Pro, abbreviated EDP, supplied as a 20 mg lyophilized vial. It belongs to the family of short peptide bioregulators developed at the St Petersburg Institute of Bioregulation and Gerontology under Vladimir Khavinson, whose programme derived low-molecular-weight peptide fractions from animal tissues and then identified short synthetic sequences intended to reproduce their activity.
Within that family Crystagen is catalogued as the immune-system peptide, the synthetic counterpart of the thymic preparations represented in our range by Thymalin. Its structural relatives are easy to place: Vilon is the Lys-Glu dipeptide associated with the same tissue, while Cortagen (Ala-Glu-Asp-Pro), Cardiogen (Ala-Glu-Asp-Arg) and Bronchogen (Ala-Glu-Asp-Leu) share the Ala-Glu-Asp core. Crystagen's own sequence overlaps with Cortagen's final three residues, which makes the pair useful in comparative work.
Specifications
Identity
- Molecular formula
- C14H21N3O8
- Molecular weight
- 359.33 g/mol
- Amino acid sequence
- Glu-Asp-Pro (EDP), linear tripeptide with free N- and C-termini
- Peptide class
- Khavinson short-peptide bioregulator (tripeptide)
Supply & purity
- Form
- Lyophilized powder in a sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Solubility
- Bacteriostatic or sterile water; readily soluble in aqueous buffers
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, protected from light; use within the study window
Additional detail
- Available size
- 20 mg
- Tissue association
- Immune-system peptide preparations; synthetic counterpart to thymic fractions
- Sequence relationship
- Corresponds to the C-terminal three residues of Cortagen (Ala-Glu-Asp-Pro)
- Charge character
- Two acidic side chains (Glu, Asp) plus a conformationally restrictive proline — strongly anionic at neutral pH
- Research areas
- Immune-cell models, lymphocyte function assays, chromatin and gene-expression studies, rodent ageing models
Working out the concentration
The vial sizes above — 20 mg — describe a mass of material, not a strength. Choose a diluent volume, work it out with the reconstitution calculator, and you have the concentration for your own vial of Crystagen plus the volume that carries any mass you want to withdraw.
For work specified in µM or nM rather than mg/mL, feed 359.33 g/mol and your volume into the peptide molarity calculator.
Certificate of analysis
Every lot of Crystagen is released against a certificate of analysis: the batch-specific laboratory data for that lot, not a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.
Purity: ≥99% by HPLC — the specification for this listing. The figure for the lot you receive is the one reported on that lot’s certificate.
No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.
Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.
Questions about Crystagen
What is Crystagen's sequence?
It is the linear tripeptide Glu-Asp-Pro, abbreviated EDP, with free N- and C-termini and a calculated mass of about 359.3 g/mol. The sequence corresponds to the final three residues of Cortagen, which makes the two useful to compare directly.
How does it differ from Thymalin?
Thymalin is a tissue-derived polypeptide complex containing many peptide species and has no single defined mass or sequence. Crystagen is one defined synthetic tripeptide. They are associated with the same tissue system, but chemically they are entirely different kinds of material.
What purity documentation is supplied?
Each lot is analysed by reverse-phase HPLC to at least 99% purity with mass-spectrometric identity confirmation, and a lot-matched certificate of analysis is available on request against the vial's lot number. Mass spectrometry matters here because short peptides absorb UV weakly.
How should it be reconstituted and stored?
It dissolves readily in bacteriostatic or sterile water with gentle swirling; no organic solvent is required. Keep the lyophilized vial at −20 °C away from light and moisture, and hold reconstituted solution at 2–8 °C, protected from light, for the duration of the study window.
