- ≥99% by HPLC per vial; separate lot-matched COA for each
- Lot-matched certificate of analysis
- Ships next business day, tracked
Metabolic Stack (Semaglutide · AOD-9604 · MOTS-c vials)
Three-vial metabolic kit: semaglutide, AOD-9604 and MOTS-c as separate vials
- FormLyophilized powder in each vial, individually capped
- Research areasIncretin receptor signalling, adipose and lipid models, AMPK and mitochondrial metabolism
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
The Metabolic Stack supplies three peptides from distinct branches of metabolic research — semaglutide, AOD-9604 and MOTS-c — as three separately sealed lyophilized vials. Each acts through a different biological system, and the kit is designed for study panels that need to keep those systems separable rather than confounded in a single preparation.
Semaglutide is a long-acting GLP-1 receptor agonist built on the native incretin backbone with an aminoisobutyric acid substitution at position 8 to resist DPP-4 cleavage and a C18 fatty diacid side chain that binds serum albumin. AOD-9604 is unrelated to incretin biology: it is a modified fragment corresponding to residues 176-191 of human growth hormone with an added N-terminal tyrosine, investigated for lipid-related activity separable from the receptor-mediated growth effects of the intact hormone. MOTS-c is a 16-residue peptide encoded within the mitochondrial 12S rRNA gene and studied in relation to AMPK signalling and mitochondrial metabolism.
Every vial is HPLC-assayed to ≥99% purity with its own lot-matched certificate of analysis. Supplied unmixed, the three can be run as independent arms, as controls for each other, or in whatever combination a protocol specifies. Research use only.
Specifications
Supply & purity
- Form
- Lyophilized powder in each vial, individually capped
- Purity
- ≥99% by HPLC per vial; separate lot-matched COA for each
Handling & storage
- Storage (lyophilized)
- −20 °C, protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, protected from light
Additional detail
- Product type
- Multi-vial research kit — three separately sealed vials
- Kit contents
- One semaglutide vial, one AOD-9604 vial, one MOTS-c vial
- Semaglutide
- CAS 910463-68-2 · C187H291N45O59 · 4113.58 g/mol
- AOD-9604
- CAS 221231-10-3 · C78H123N23O23S2 · 1815.08 g/mol
- MOTS-c
- CAS 1627580-64-6 · C101H152N28O22S2 · 2174.55 g/mol
- Semaglutide class
- Acylated GLP-1 receptor agonist with Aib substitution at position 8
- MOTS-c class
- Mitochondrial-derived peptide, 16 residues, encoded in 12S rRNA
- Research areas
- Incretin receptor signalling, adipose and lipid models, AMPK and mitochondrial metabolism
- Reconstitution
- Each vial prepared separately at protocol-defined concentration
Questions about Metabolic Stack (Semaglutide · AOD-9604 · MOTS-c vials)
Why are these three grouped together?
Because they represent three separate metabolic mechanisms — GLP-1 receptor agonism, a growth hormone fragment analogue and a mitochondrial-derived peptide. A panel spanning receptor signalling, adipose handling and mitochondrial energetics gives broader coverage than three variations on one pathway.
Does each vial have its own certificate of analysis?
Yes. Each vial is a distinct manufacturing lot released with its own COA reporting HPLC identity and purity for that peptide. Three separate documents accompany the kit, and current lot COAs can be requested before you place an order.
How should semaglutide be reconstituted?
Slowly and gently. It is a large acylated peptide that is sensitive to shear, so bacteriostatic water should run down the inner vial wall rather than onto the cake, and the vial should be swirled rather than shaken. Foaming indicates handling that risks peptide loss.
Can components be used at different times?
Yes, and that flexibility is the reason for a multi-vial format. Unopened lyophilized vials stored sealed at −20 °C away from light and moisture stay stable well beyond a year, so a protocol can stage components across phases of a study.
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