- ≥99% HPLC purity
- Lot-matched certificate of analysis
- Ships next business day, tracked
Argireline Serum 10%
Aqueous acetyl hexapeptide-8 serum at 10% concentrate loading, 30 mL
- FormClear, low-viscosity aqueous serum in a 30 mL bottle
- Research areasSNARE complex assembly, exocytosis interference, expression-line formulation studies, peptide permeation and vehicle effects
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
This is a ready-made aqueous serum built around acetyl hexapeptide-8, the cosmetic signal peptide marketed under the Argireline name, supplied in a 30 mL bottle. The active is the N-acetylated, C-terminally amidated hexapeptide Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2, CAS 616204-22-9, molecular weight about 889 g/mol. It is the same material we supply as lyophilized powder in 10 mg and 50 mg vials, released against a lot-matched certificate of analysis.
The 10% designation follows cosmetic-formulation convention: it refers to the loading of the acetyl hexapeptide-8 concentrate in the finished serum, not to 10% free peptide by mass. Trade-grade peptide concentrates are themselves dilute aqueous solutions, so actual free-peptide content in the bottle is correspondingly lower and is stated on the lot label and certificate. Reading the percentage as literal peptide mass is one of the most common errors in this category, and we would rather state the convention plainly than let the number mislead.
Specifications
Supply & purity
- Form
- Clear, low-viscosity aqueous serum in a 30 mL bottle
Additional detail
- Available size
- 30 mL
- Labelled strength
- 10% acetyl hexapeptide-8 concentrate loading; free-peptide content is lower and is stated per lot
- Active
- Acetyl hexapeptide-8 (Argireline), synthetic cosmetic signal peptide
- INCI name of active
- Acetyl Hexapeptide-8 (formerly acetyl hexapeptide-3)
- CAS number (active)
- 616204-22-9
- Molecular formula (active)
- C34H60N14O12S
- Molecular weight (active)
- 888.99 g/mol
- Amino acid sequence (active)
- Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
- Peptide purity input
- ≥99% by HPLC with mass-spectrometric identity check; lot-matched COA available
- Vehicle
- Aqueous, low viscosity, no added fragrance or colourant
- Research areas
- SNARE complex assembly, exocytosis interference, expression-line formulation studies, peptide permeation and vehicle effects
- Stability note
- The methionine residue oxidises readily in solution; keep cold, dark and tightly closed
- Storage
- 2–8 °C preferred, protected from light; do not freeze
Questions about Argireline Serum 10%
Does 10% mean 10% peptide by weight?
No. In cosmetic formulation the percentage conventionally refers to the loading of the peptide concentrate, and those concentrates are themselves dilute aqueous solutions. Actual free acetyl hexapeptide-8 content is substantially lower and is stated on the lot label and certificate of analysis.
Why does this need refrigeration when the powder does not?
Because the methionine residue oxidises far faster in solution than in the lyophilized state. Cold, dark, tightly closed storage slows sulfoxide formation. The powder is stable frozen for much longer, which is why studies needing extended shelf life usually work from vials.
Is a certificate of analysis available?
Yes. The peptide used in manufacture is analysed by reverse-phase HPLC to ≥99% purity with mass-spectrometric identity confirmation, and a lot-matched COA is available on request. Quote the batch code printed on the bottle.
How does this compare with the Argireline vials?
Same molecule, different presentation. The vials supply 10 mg or 50 mg of lyophilized powder for researchers building their own vehicle at a defined concentration; this serum is a ready-made aqueous formulation for work where the finished vehicle is what is under test.
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