- ≥99% HPLC purity
- Lot-matched certificate of analysis
- Ships next business day, tracked
CoQ10 (Ubiquinone) Injection
Solubilized ubiquinone at 30 mg/mL in a 10 mL vial for mitochondrial research
- Mol. weight863.34 g/mol
- Research areasMitochondrial bioenergetics, oxidative stress and lipid peroxidation, statin-associated CoQ10 depletion, mitochondrial myopathy models
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
Coenzyme Q10, chemically 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone, is the lipid-soluble electron carrier that shuttles electrons from complexes I and II to complex III in the mitochondrial respiratory chain. Its benzoquinone head cycles between the oxidised ubiquinone form supplied here, the ubisemiquinone radical and the fully reduced ubiquinol, while a ten-unit polyisoprenoid tail anchors it inside the inner mitochondrial membrane.
Specifications
Identity
- CAS number
- 303-98-0
- Molecular formula
- C59H90O4
- Molecular weight
- 863.34 g/mol
Supply & purity
- Solubility
- Practically insoluble in water; formulated with a solubilising carrier for aqueous use
Additional detail
- Concentration
- 30 mg/mL ubiquinone
- Vial size
- 10 mL (300 mg total content)
- Also known as
- Coenzyme Q10, ubiquinone, ubidecarenone, CoQ10
- Chemical class
- 1,4-benzoquinone with a ten-unit polyisoprenoid side chain
- Redox states
- Ubiquinone (oxidised) ⇄ ubisemiquinone ⇄ ubiquinol (reduced)
- Biochemical role
- Electron carrier between respiratory complexes I/II and III; membrane-phase antioxidant
- Research areas
- Mitochondrial bioenergetics, oxidative stress and lipid peroxidation, statin-associated CoQ10 depletion, mitochondrial myopathy models
- Storage
- 2–8 °C preferred, tightly sealed and protected from light; do not freeze
Questions about CoQ10 (Ubiquinone) Injection
Is this ubiquinone or ubiquinol?
This is ubiquinone, the oxidised form, which is the more stable of the two for storage. Ubiquinol is the reduced form and is readily oxidised in air. Cells interconvert the two enzymatically, so the redox state supplied matters mainly for stability and for analytical work.
Why is light protection emphasised?
The benzoquinone head group is photolabile and degrades on exposure to light, which changes both content and the visible colour of the solution. Keeping the vial in its carton or wrapped, and minimising bench time under lighting, preserves the stated concentration over the working window.
What documentation comes with the vial?
A lot-matched certificate of analysis is available covering identity and content of the coenzyme Q10 used. Retaining that COA with your records lets analytical results be traced back to the specific lot the data were generated with.
Related
