- ≥99% by HPLC
- Lot-matched certificate of analysis
- Ships next business day, tracked
NMN (Nicotinamide Mononucleotide)
Direct NAD+ salvage-pathway precursor — powder, capsules or research vial
- FormCrystalline white powder; also supplied as capsules or in a sealed vial
- Mol. weight334.22 g/mol
- Research areasNAD+ salvage pathway, sirtuin and PARP biology, mitochondrial metabolism, vascular and metabolic ageing models
Overview
Nicotinamide mononucleotide (NMN) is a pyridine nucleotide and the immediate biosynthetic precursor of NAD+ in the mammalian salvage pathway. It is a small molecule rather than a peptide: CAS 1094-61-7, molecular formula C11H15N2O8P, molecular weight 334.22 g/mol. NAMPT, the rate-limiting salvage enzyme, converts nicotinamide and PRPP into NMN; the NMNAT1–3 adenylyltransferases then add an adenylyl group from ATP to produce NAD+.
Three presentations are listed and they serve different work: 500 mg of crystalline powder for laboratories weighing their own stocks, 250 mg capsules in bottles of sixty where a fixed unit content is wanted, and a 500 mg vial of injectable-grade material for solution work. The powder is hygroscopic, so containers are brought to room temperature before opening to avoid condensation, and aqueous solutions are prepared fresh, since the compound hydrolyses faster when warm or alkaline. Research using it concentrates on NAD+ salvage flux, sirtuin and PARP biology, mitochondrial metabolism, and vascular and metabolic ageing models, frequently alongside nicotinamide riboside and NAD+ itself so that precursor loading and direct coenzyme supply can be compared within one system.
Specifications
Identity
- CAS number
- 1094-61-7
- Molecular formula
- C11H15N2O8P
- Molecular weight
- 334.22 g/mol
Supply & purity
- Form
- Crystalline white powder; also supplied as capsules or in a sealed vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Solubility
- Freely soluble in water; solutions prepared fresh where assay accuracy matters
Additional detail
- Also known as
- Nicotinamide mononucleotide, beta-NMN, NAMN's amide counterpart
- Chemical class
- Pyridine nucleotide (nicotinamide riboside 5'-phosphate)
- Biosynthetic position
- Product of NAMPT; substrate of NMNAT1–3 in NAD+ synthesis
- Research areas
- NAD+ salvage pathway, sirtuin and PARP biology, mitochondrial metabolism, vascular and metabolic ageing models
- Storage (powder)
- −20 °C, sealed and protected from light and moisture; hygroscopic
- Storage (in solution)
- 2–8 °C, used promptly; hydrolyses faster when warm or alkaline
- Regulatory status
- Not a drug and, per FDA's stated position, excluded from the dietary supplement definition
Units and conversions
The arithmetic on an oral format is unit arithmetic rather than dilution arithmetic. Use the milligram to microgram converter to line a per-unit figure up against a method written in different units.
Certificate of analysis
Every lot of NMN (Nicotinamide Mononucleotide) is released against a certificate of analysis: the batch-specific laboratory data for that lot, not a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.
Purity: ≥99% by HPLC — the specification for this listing. The figure for the lot you receive is the one reported on that lot’s certificate.
No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.
Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.
Questions about NMN (Nicotinamide Mononucleotide)
How does NMN differ from NR and from NAD+ itself?
NMN is one enzymatic step from NAD+, requiring only adenylylation by NMNAT. Nicotinamide riboside sits one step earlier and must be phosphorylated first. NAD+ is the intact dinucleotide. Comparative studies of the three are a standard part of salvage-pathway research.
Is NMN third-party tested?
Yes. Each lot is analysed by an independent laboratory using HPLC to confirm ≥99% purity with identity testing, and a lot-matched Certificate of Analysis is available for the batch supplied. Check that the lot number on the container matches the COA.
How should NMN be stored?
Keep the powder sealed at −20 °C away from light and moisture — it is hygroscopic and picks up water readily. Let containers warm before opening to avoid condensation, and prepare aqueous solutions fresh, holding them at 2–8 °C for short periods only.
Is NMN a peptide?
No. It is a pyridine nucleotide — nicotinamide riboside bearing a 5'-phosphate — with the formula C11H15N2O8P. It appears in this catalogue because it features in the same mitochondrial and longevity research programmes as many of the peptides listed.
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