- ≥99% by HPLC; lot-matched COA available
- Lot-matched certificate of analysis
- Ships next business day, tracked
NMN (Nicotinamide Mononucleotide)
Direct NAD+ salvage-pathway precursor — powder, capsules or research vial
- FormCrystalline white powder; also supplied as capsules or in a sealed vial
- Mol. weight334.22 g/mol
- Research areasNAD+ salvage pathway, sirtuin and PARP biology, mitochondrial metabolism, vascular and metabolic ageing models
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
Nicotinamide mononucleotide (NMN) is a pyridine nucleotide and the immediate biosynthetic precursor of NAD+ in the mammalian salvage pathway. It is a small molecule rather than a peptide: CAS 1094-61-7, molecular formula C11H15N2O8P, molecular weight 334.22 g/mol. NAMPT, the rate-limiting salvage enzyme, converts nicotinamide and PRPP into NMN; the NMNAT1–3 adenylyltransferases then add an adenylyl group from ATP to produce NAD+.
Specifications
Identity
- CAS number
- 1094-61-7
- Molecular formula
- C11H15N2O8P
- Molecular weight
- 334.22 g/mol
Supply & purity
- Form
- Crystalline white powder; also supplied as capsules or in a sealed vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Solubility
- Freely soluble in water; solutions prepared fresh where assay accuracy matters
Additional detail
- Also known as
- Nicotinamide mononucleotide, beta-NMN, NAMN's amide counterpart
- Chemical class
- Pyridine nucleotide (nicotinamide riboside 5'-phosphate)
- Biosynthetic position
- Product of NAMPT; substrate of NMNAT1–3 in NAD+ synthesis
- Research areas
- NAD+ salvage pathway, sirtuin and PARP biology, mitochondrial metabolism, vascular and metabolic ageing models
- Storage (powder)
- −20 °C, sealed and protected from light and moisture; hygroscopic
- Storage (in solution)
- 2–8 °C, used promptly; hydrolyses faster when warm or alkaline
- Regulatory status
- Not a drug and, per FDA's stated position, excluded from the dietary supplement definition
Questions about NMN (Nicotinamide Mononucleotide)
How does NMN differ from NR and from NAD+ itself?
NMN is one enzymatic step from NAD+, requiring only adenylylation by NMNAT. Nicotinamide riboside sits one step earlier and must be phosphorylated first. NAD+ is the intact dinucleotide. Comparative studies of the three are a standard part of salvage-pathway research.
Is NMN third-party tested?
Yes. Each lot is analysed by an independent laboratory using HPLC to confirm ≥99% purity with identity testing, and a lot-matched Certificate of Analysis is available for the batch supplied. Check that the lot number on the container matches the COA.
Why is NMN sold as a research chemical rather than a supplement?
Because the FDA has stated that NMN falls outside the dietary supplement definition on the basis that it was authorised for investigation as a new drug. MyPeptide therefore catalogues it strictly as a laboratory research chemical.
How should NMN be stored?
Keep the powder sealed at −20 °C away from light and moisture — it is hygroscopic and picks up water readily. Let containers warm before opening to avoid condensation, and prepare aqueous solutions fresh, holding them at 2–8 °C for short periods only.
Is NMN a peptide?
No. It is a pyridine nucleotide — nicotinamide riboside bearing a 5'-phosphate — with the formula C11H15N2O8P. It appears in this catalogue because it features in the same mitochondrial and longevity research programmes as many of the peptides listed.
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