- ≥99% HPLC purity
- Lot-matched certificate of analysis
- Ships next business day, tracked
GHK-Cu Cream
1% GHK-Cu in an emollient cream base — 30 g and 50 g research jars
- FormBlue-tinted emollient cream in a screw-top jar
- Research areasVehicle and occlusion effects, ECM and fibroblast models, copper-peptide stability
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
This preparation places GHK-Cu, the copper(II) complex of glycyl-L-histidyl-L-lysine, into an emollient cream base at 1% — roughly 10 mg of the complex per gram. Where an aqueous serum is designed to deposit active and evaporate, a cream leaves an occlusive residual film. That difference is not cosmetic trivia in a research context: occlusion changes hydration of the stratum corneum, alters partitioning of a hydrophilic complex and typically extends contact time, all of which affect what a permeation or skin-model experiment measures.
GHK-Cu itself is one of the most heavily documented copper peptides. The tripeptide was isolated from human plasma in the 1970s, binds copper with high affinity, and has been studied in fibroblast culture, wound models and gene-expression surveys for its relationship to matrix turnover and antioxidant chemistry. Supplying it in a cream base gives laboratories a vehicle-controlled counterpart to the aqueous serum for side-by-side vehicle comparisons.
Two jar sizes are stocked, 30 g and 50 g, both at 1% GHK-Cu. Peptide input is third-party tested to ≥99% by HPLC with a lot-matched certificate of analysis. Filled and shipped from the United States for laboratory research only.
Specifications
Supply & purity
- Form
- Blue-tinted emollient cream in a screw-top jar
- Available sizes
- 30 g · 1% GHK-Cu; 50 g · 1% GHK-Cu
Additional detail
- Active concentration
- 1% w/w GHK-Cu, approximately 10 mg per gram
- Active
- GHK-Cu, copper(II) complex of glycyl-L-histidyl-L-lysine
- INCI name of active
- Copper Tripeptide-1
- CAS number (active)
- 89030-95-5
- Molecular formula (active)
- C14H24N6O4·Cu
- Molecular weight (active)
- 403.93 g/mol
- Peptide purity input
- ≥99% by HPLC; lot-matched COA available
- Vehicle
- Emollient oil-in-water cream base, no added fragrance
- Research areas
- Vehicle and occlusion effects, ECM and fibroblast models, copper-peptide stability
- Storage
- Cool and dark, ideally 2–8 °C; keep the jar closed
- Compatibility note
- Avoid mixing with strong reducing agents or chelators that disturb copper coordination
Questions about GHK-Cu Cream
What concentration of GHK-Cu does the cream contain?
Both jar sizes are formulated at 1% w/w GHK-Cu, approximately 10 mg of the copper tripeptide complex per gram of cream. The 30 g and 50 g options differ only in fill weight, so a study can scale up without changing the formulation.
How does the cream differ from the GHK-Cu serum?
The active is identical; the vehicle is not. The cream is an emollient emulsion that occludes and prolongs contact, while the serum is a thin aqueous base that dries quickly. Comparing the two at matched concentration is a standard way to isolate vehicle effects in skin-model research.
Is the peptide in this formulation tested, and is a COA available?
Yes. The peptide input is released against a ≥99% HPLC purity specification with mass-spectrometric identity confirmation, and the lot-matched certificate of analysis is available on request. Each finished container is labelled with its own lot number so bench records can be tied back to the raw-material certificate.
Why does the cream have a blue tint?
The colour comes from the coordinated copper(II) ion, not from an added dye. An intact GHK-Cu complex is blue, so the tint doubles as a rough integrity check: fading or a shift toward green suggests the copper coordination has been disturbed.
How should the jars be stored and sampled?
Keep them closed, cool and dark, ideally refrigerated. Sample with a clean spatula each time rather than dipping used tools, weigh out quantities for quantitative work, and log the lot number and opening date so results can be tied back to a specific fill.
Can the cream be combined with other actives?
Any addition should be checked for compatibility first. Strong reducing agents such as high-concentration ascorbic acid, and chelating excipients, can compete for the copper and change the species actually present. Analytical confirmation is preferable to assuming the complex has survived.
What does research use only mean for a topical formulation?
This preparation is supplied as a laboratory research material for bench and model work such as ex vivo skin, reconstructed epidermis or stability testing. It is not a licensed cosmetic, drug or medical device, has not been reviewed by the FDA, and is not intended for human or veterinary application.
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