- ≥99% per component by HPLC; lot-matched COA
- Lot-matched certificate of analysis
- Ships next business day, tracked
GHK-Cu + Epitalon
Co-formulated blend vial: 50 mg GHK-Cu with 10 mg epitalon
- FormCo-lyophilized powder, sealed glass vial
- Research areasExtracellular matrix remodeling, skin and hair-follicle models, telomerase and senescence research
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
This blend supplies two well-characterized research peptides in a single lyophilized vial: 50 mg of GHK-Cu, the copper-binding tripeptide, together with 10 mg of epitalon, the Ala-Glu-Asp-Gly bioregulator tetrapeptide. Laboratories that run parallel skin-remodeling and cellular-aging work often prefer a co-formulated vial because it removes one reconstitution step and keeps the ratio between the two compounds fixed across a study.
GHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine, a tripeptide isolated from human plasma in the 1970s. It is studied for reported effects on collagen and glycosaminoglycan gene expression, wound-model closure and antioxidant enzyme regulation, and it carries copper in a form that fibroblast cultures can take up. Epitalon is a synthetic analogue of the pineal preparation epithalamin, examined in telomerase, chromatin and circadian research.
The two are combined in research settings because they act on different levels of the same broad question: extracellular matrix remodeling on one side and nuclear or telomere-associated processes on the other. Blend content is verified for both components with a lot-matched Certificate of Analysis. For laboratory research use only.
Specifications
Supply & purity
- Form
- Co-lyophilized powder, sealed glass vial
- Purity
- ≥99% per component by HPLC; lot-matched COA
Handling & storage
- Storage (lyophilized)
- −20 °C, protected from light and moisture
Additional detail
- Vial content
- 60 mg total — GHK-Cu 50 mg + epitalon 10 mg
- Component ratio
- 5:1 by mass (GHK-Cu : epitalon)
- GHK-Cu CAS number
- 89030-95-5
- GHK-Cu molecular formula
- C14H24N6O4·Cu
- GHK-Cu molecular weight
- 403.93 g/mol
- GHK-Cu sequence
- Gly-His-Lys, copper(II) complex
- Epitalon CAS number
- 307297-39-8
- Epitalon molecular formula
- C14H22N4O9
- Epitalon sequence
- H-Ala-Glu-Asp-Gly-OH (390.35 g/mol)
- Research areas
- Extracellular matrix remodeling, skin and hair-follicle models, telomerase and senescence research
Questions about GHK-Cu + Epitalon
What is in this blend?
Each vial contains 60 mg of co-lyophilized material: 50 mg of GHK-Cu, the copper-binding tripeptide, and 10 mg of epitalon, the Ala-Glu-Asp-Gly tetrapeptide. Both components are verified individually on the lot-matched Certificate of Analysis.
Why is the powder blue?
The color comes from the copper(II) ion coordinated by the GHK tripeptide. A blue to blue-violet cake is expected for any GHK-Cu preparation; loss of that color can indicate reduction or degradation of the copper complex.
Can the two components be varied independently?
Not in this format. Reconstituting a co-lyophilized vial fixes the 5:1 mass ratio, so any dilution changes both concentrations together. Studies that need to vary one compound alone should use separate GHK-Cu and epitalon vials.
Is the blend third-party tested?
Yes. Purity is confirmed by HPLC for each component and identity by mass spectrometry, with a lot-matched Certificate of Analysis available before purchase documenting the content of both peptides in the vial.
What should not be mixed with this blend?
Avoid strong reducing agents and thiol-containing reagents such as dithiothreitol or glutathione, which can reduce copper(II) and destabilize the complex. Also avoid strongly alkaline buffers, which can precipitate copper species out of solution.
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