- ≥99% by HPLC; lot-matched COA available
- Lot-matched certificate of analysis
- Ships next business day, tracked
GHRP-2
Pralmorelin — synthetic GHS-R1a hexapeptide secretagogue
- FormLyophilized powder, sealed glass vial
- Mol. weight817.97 g/mol
- Research areasGHS-R1a pharmacology, secretagogue potency ranking, neuroendocrine signalling
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
GHRP-2, also catalogued as pralmorelin, is a synthetic hexapeptide agonist of the growth hormone secretagogue receptor GHS-R1a. Its sequence — D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 — descends from the enkephalin-derived GHRP-6 scaffold, with a D-2-naphthylalanine at position 2 that markedly increased potency and a D-alanine at the N-terminus that blunts aminopeptidase attack.
Historically GHRP-2 was one of the compounds that established the growth hormone secretagogue receptor as a distinct target from the GHRH receptor, years before ghrelin was identified as the natural ligand. That lineage makes it a useful reference agonist: laboratories use it to characterise GHS-R1a binding, to calibrate calcium-flux and inositol-phosphate assays, and to compare potency across the GHRP family alongside ipamorelin, GHRP-6 and hexarelin.
Specifications
Identity
- CAS number
- 158861-67-7
- Molecular formula
- C45H55N9O6
- Molecular weight
- 817.97 g/mol
- Amino acid sequence
- D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
- Chain length
- 6 residues, C-terminal amide
- Peptide class
- Growth hormone releasing peptide (GHRP), GHS-R1a agonist
Supply & purity
- Form
- Lyophilized powder, sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Available sizes
- 5 mg, 10 mg
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, used within the study window
Additional detail
- Also known as
- Pralmorelin, KP-102, GPA-748
- Research areas
- GHS-R1a pharmacology, secretagogue potency ranking, neuroendocrine signalling
Questions about GHRP-2
What is GHRP-2?
GHRP-2, or pralmorelin, is a synthetic hexapeptide agonist of the growth hormone secretagogue receptor GHS-R1a. It is used in laboratories as a potent reference agonist for receptor binding, calcium signalling and comparative secretagogue studies.
How does GHRP-2 compare with GHRP-6?
Both are hexapeptides acting at GHS-R1a, but GHRP-2 carries a D-2-naphthylalanine at position 2 and is generally reported as the more potent of the two in molar terms. GHRP-6 is more strongly associated with appetite signalling in animal models.
Do you provide a Certificate of Analysis?
Yes. Every lot is third-party tested by HPLC for ≥99% purity and identity, and a lot-matched Certificate of Analysis is available on request. Match the lot number on the vial to the certificate before entering the material into your records.
What sizes are available?
GHRP-2 is offered in 5 mg and 10 mg lyophilized vials. The 5 mg vial is convenient for assay development and short in vitro series, while 10 mg lowers the per-milligram cost for extended comparative studies across the secretagogue family.
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