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- Lot-matched certificate of analysis
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HMG (Menotropins) 75 IU — Prescription Reference
Urinary-derived gonadotropin preparation with FSH and LH activity — Rx only
- FormLyophilized powder in a sealed vial, reconstituted with the supplied or specified diluent
Supplied for laboratory research use only. Not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
Overview
This is a prescription-only biologic listed for institutional reference. Human menopausal gonadotropin, or menotropins, is supplied only against a valid prescription or documented institutional authorisation, and this entry exists so that catalogue users can see specification and handling information. It is not offered for open sale, and no sourcing, dosing or administration guidance is provided here.
Menotropins is a gonadotropin preparation purified from the urine of postmenopausal women, catalogued under CAS 61489-71-2 and standardised by bioassay rather than by mass. A conventional vial supplies 75 IU of follicle-stimulating hormone activity together with 75 IU of luteinising hormone activity. Both are glycoprotein hormones sharing a common alpha subunit with a hormone-specific beta subunit, and in highly purified preparations a portion of the LH activity is contributed by chorionic gonadotropin present in the source material — which is why potency is expressed in international units against a reference standard.
Specifications
Identity
- CAS number
- 61489-71-2
Supply & purity
- Form
- Lyophilized powder in a sealed vial, reconstituted with the supplied or specified diluent
- Available sizes
- 75 IU vial; 75 IU × 5 pack
Handling & storage
- Storage (lyophilized)
- Per approved labelling — commonly refrigerated or at controlled room temperature, protected from light
- Storage (reconstituted)
- Refrigerated and used within the period stated in the approved labelling
Additional detail
- Regulatory status
- Prescription-only medicine; supplied exclusively against valid prescription or institutional authorisation
- Product type
- Human menopausal gonadotropin (menotropins), a urinary-derived glycoprotein hormone preparation
- Potency basis
- International units assigned by bioassay against an international reference standard, not by mass
- Activity per vial
- 75 IU follicle-stimulating hormone activity with 75 IU luteinising hormone activity
- Source
- Purified from urine of postmenopausal women
- Molecular nature
- Heterodimeric glycoprotein hormones — a common alpha subunit paired with a hormone-specific beta subunit, extensively glycosylated
- Receptor targets
- FSH receptor and the luteinising hormone/choriogonadotropin receptor (LHCGR)
- Approved indication areas
- Assisted reproductive technology and, per individual product licence, ovulation induction — as stated in approved labelling
- Supply condition
- Dispensed only against valid authorisation; no dosing or administration guidance supplied by MyPeptide
Questions about HMG (Menotropins) 75 IU — Prescription Reference
Can I buy HMG from this page?
No. This is a prescription-only biologic and this entry is a reference listing for institutional catalogue use. It can be supplied only against a valid prescription or documented institutional authorisation, and we provide no sourcing route, dosing information or administration guidance for it.
Why is HMG measured in IU rather than milligrams?
Because it is a purified biological preparation containing heterogeneously glycosylated glycoprotein isoforms, equal masses do not carry equal biological activity. International units assigned by bioassay against an international reference standard express activity directly, and the assayed value for the specific lot is what governs.
What are its approved uses?
As a matter of public regulatory record, menotropin products are approved for use in assisted reproductive technology — development of multiple follicles in appropriately selected patients — and, depending on the individual product licence, for ovulation induction. Approved labelling for the specific product is the authoritative source.
How does it differ from recombinant FSH?
Recombinant FSH is produced in cell culture and contains FSH activity only. Menotropins is purified from urine and delivers both FSH and LH activity, with part of the LH activity in highly purified products contributed by chorionic gonadotropin from the source. That pharmacological difference is the subject of most published comparisons.
How does it relate to HCG and gonadorelin?
All three act on the reproductive axis at different points. Gonadorelin is GnRH, acting on the pituitary upstream; HCG is an LHCGR agonist with a long half-life; menotropins delivers both FSH and LH activity directly to the gonad. They are pharmacologically distinct and not interchangeable.
What documentation accompanies a supplied vial?
Where supply is authorised, vials arrive with manufacturer labelling stating assayed potency in international units, lot number and expiry, together with the approved product information. Documentation, storage and dispensing records are handled under the receiving institution's own quality controls.
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