- Lot-matched certificate of analysis
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Sexual Health & Hormonal Peptides
PT-141 Nasal Spray
Pre-mixed bremelanotide solution in a 15 mL metered nasal pump
- FormAqueous solution, 15 mL amber bottle with metered nasal pump
- Research areasIntranasal peptide delivery, mucosal absorption, formulation stability, melanocortin pharmacology
Overview
This is PT-141 (bremelanotide) supplied as a ready-mixed aqueous solution in a 15 mL amber bottle fitted with a metered nasal pump. The peptide itself is identical to the material in our lyophilized vials — a cyclic heptapeptide melanocortin agonist with MC3R and MC4R preference — but it is presented as a pre-dissolved intranasal format so that researchers evaluating mucosal delivery do not have to reconstitute and transfer powder themselves.
The cyclic architecture that makes bremelanotide robust is also what makes a pre-mixed aqueous format practical for it. The ring is closed by a lactam bond between aspartate and lysine side chains rather than by a disulfide, so there is no thiol-exchange chemistry to manage in solution, and the acetylated N-terminus, the norleucine and the D-phenylalanine all slow exopeptidase attack. Fills are 10 mg or 20 mg in 15 mL, giving nominal strengths near 0.67 and 1.33 mg/mL. Work in this format tends to be about the route rather than the molecule: deposition, mucosal residence and clearance, formulation stability across a study period, and comparison against the sublingual troche and the reconstituted vial listed alongside it.
Specifications
Identity
- Peptide class
- Cyclic heptapeptide melanocortin (MC3R/MC4R) agonist
Supply & purity
- Form
- Aqueous solution, 15 mL amber bottle with metered nasal pump
- Available sizes
- 15 mL containing 10 mg; 15 mL containing 20 mg
Additional detail
- Nominal concentration
- ≈0.67 mg/mL (10 mg fill) or ≈1.33 mg/mL (20 mg fill)
- Active component
- PT-141 (bremelanotide), ≥99% by HPLC
- CAS number (active)
- 189691-06-3
- Molecular formula (active)
- C50H68N14O10
- Molecular weight (active)
- 1025.16 g/mol
- Vehicle
- Aqueous, preserved for multi-draw handling; clear and colourless when fresh
- Purity documentation
- Lot-matched COA for the peptide used in the fill
- Research areas
- Intranasal peptide delivery, mucosal absorption, formulation stability, melanocortin pharmacology
- Storage
- 2–8 °C upright, protected from light; do not freeze the filled bottle
Units and conversions
This is a pre-mixed presentation: the strength is fixed at fill, and the only arithmetic between the label and the bench is a change of units. The peptide unit converter moves between mg, mcg, mL and µL without the decimal-point slip that costs a whole run.
Certificate of analysis
Every lot of PT-141 Nasal Spray is released against its own lot documentation, and where the manufacturer issues a certificate of analysis for it, that certificate is the record for the lot rather than a generic document for the compound. The lot number on the certificate matches the lot number printed on the label you receive — the vial label itself, where the product is vialled — so the record and the material it describes can always be reconciled.
This listing carries no purity percentage, so none is claimed for it here. Where the manufacturer issues analytical documentation for a lot of this item, it is passed on unaltered — ask and we will send whatever exists.
No lot certificate is on display on this page at the moment. That is a publishing state and not a testing one: lots are released and documented as described above whether or not the document is posted here, and we will send what exists for the lot in stock, or for a lot already on your bench, by its number.
Certificates are available on request before you order as well as after, with no account and no charge. Request the certificate for this listing, read the testing and documentation policy in full, or see how to read a peptide COA.
Questions about PT-141 Nasal Spray
How much PT-141 is in each bottle?
Both options are 15 mL. One is filled with 10 mg of PT-141 and the other with 20 mg, giving nominal solution strengths of roughly 0.67 mg/mL and 1.33 mg/mL. Actual delivered mass per actuation depends on the pump’s metered volume, which researchers should verify gravimetrically for their own records.
Do you provide a certificate of analysis?
Every bottle is traceable to a lot-matched COA covering the peptide used in the fill, including HPLC purity of ≥99% and mass-spectrometric identity confirmation. Quote the lot number printed on the label when requesting the document.
Why choose a nasal format over powder for research?
Pre-mixed solution removes reconstitution error, keeps concentration consistent across a study, and is the correct article when the research question is mucosal delivery itself — deposition, clearance, formulation stability or route comparison. For assay work where you set the concentration, the lyophilized vial is more flexible.
How should the bottle be stored, and how long does it last?
Store upright at 2–8 °C away from light, and do not freeze. Solutions degrade faster than lyophilized powder, so define an in-use period for your protocol and verify concentration analytically if the study runs long. Discard if the liquid becomes cloudy, discoloured or shows particulates.
Can this be used as a needle-free alternative for personal use?
No. Despite the familiar packaging this is a research chemical, not a consumer product. It is supplied for laboratory investigation only.
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